Treatment of two infants with PIK3CA-related overgrowth spectrum by alpelisib

Morin G, Degrugillier-Chopinet C, Vincent M, Fraissenon A, Aubert H, Chapelle C, Higuin C, Dubos F, Catteau B, Petit F, Mezel A, Domanski O, Herbreteau G, Alesandrini M, Boddaert N, Boutry N, Broissand C, Han TK, Branle F, Sarnacki S, Blanc T, Guibaud L, Canaud G

Read the publication

Treatment strategies for mosaic overgrowth syndromes of the PI3K-AKT-mTOR pathway

Gabriel Morin, Guillaume Canaud

Read the publication

Alpelisib administration reduced lymphatic malformations in a mouse model and in patients

Florence Delestre, Quitterie Venot, Charles Bayard, Antoine Fraissenon, Sophia Ladraa, Clément Hoguin, Célia Chapelle, Junna Yamaguchi, Rubina Cassaca, Lola Zerbib, Sato Magassa, Gabriel Morin, Vahid Asnafi, Patrick Villarese, Sophie Kaltenbach, Sylvie Fraitag, Jean-Paul Duong, Christine Broissand, Olivia Boccara, Véronique Soupre, Bernard Bonnotte, Caroline Chopinet, Tristan Mirault, Christophe Legendre, Laurent Guibaud, Guillaume Canaud

Read the publication

Frequent SLC35A2 brain mosaicism in mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE)

Bonduelle et al. acta neuropathol commun

Read the publication

Gradient of brain mosaic RHEB variants causes a continuum of cortical dysplasia

Annals Clinical and Translational Neurology

Read the publication